KPV (10mg)

KPV (10mg) Peptide Description 

KPV (10mg) (Lys–Pro–Val) is the C-terminal tripeptide fragment of α-melanocyte stimulating hormone (α-MSH). As a small, bioactive peptide, KPV reproduces many of α-MSH’s anti-inflammatory, antimicrobial and tissue-protective activities while avoiding full-length melanocortin receptor signaling in some contexts. In research settings KPV has been studied for:

• Potent anti-inflammatory action — suppresses pro-inflammatory cytokines and leukocyte activation.
• Antimicrobial activity — direct candidacidal and bactericidal effects reported for α-MSH C-terminal fragments including KPV.
• Mucosal and epithelial protection / wound healing — accelerates epithelial repair in corneal and other epithelial models.
• Anti-fibrotic and immunomodulatory effects — reduces fibrosis and shifts macrophage phenotypes in preclinical studies.
• Favorable safety & non-immunogenic profile in multiple animal models.

KPV is a useful research tool for studying innate immune regulation, mucosal defense and novel anti-inflammatory peptide therapeutics.

KPV (10mg) Structure

• Sequence: Lys–Pro–Val (KPV) — the C-terminal tripeptide of α-MSH (α-MSH(11–13)).
• Molecular formula (tri-peptide only): C₁₅H₂₆N₄O₄ (approximate for the free tripeptide)
• Synonyms: α-MSH(11–13), melanocortin C-terminal tripeptide, KPV.
• Form: synthetic peptide, typically supplied lyophilized for research use.

Research Areas

• Anti-inflammatory therapeutics
• Antimicrobial peptides & host defense
• Mucosal / epithelial wound healing (cornea, skin, mucosa)
• Anti-fibrotic interventions
• Peptide delivery and formulation research